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Isaiah is the first of the four major prophets (together with him Jeremiah, Ezekiel and Daniel) and is often present in the iconographic representations of the Old Testament. He lives the tragic events that occurred between 735 and 701 BC, the background of the advent of the Assyrian power in the Middle East, relating to the Jewish kings who followed one another in those years. He is represented in relation to the two prophecies he pronounced. The first - in the form of an excerpt, recognizable in the fresco on the tombstone he kept "... <lang xml:lang="it-IT">SIGNUM: ECCE VIRGO CONCIPIET</lang>, is found in chapter 7 in verse 14 whose full translation is: Therefore the Lord himself will give you a sign. Behold, a virgin shall conceive and bear a son, and shall call his name Immanuel (God with us). The second prophecy, “A shoot shall come forth from the stump of Jesse,” is at the origin of the iconographic theme of the tree of Jesse, in which the prophets Jeremiah and Isaiah are often present. The prophet – who occupies the other of the two semi-pendentives – is represented as a young, beardless man with his gaze turned to the sky; with his head partially covered by a headdress, he holds the inscribed slab in his left hand, while his right hand is turned upwards like his gaze. At his feet we read <lang xml:lang="it-IT">ISAIAS</lang>, C 7, with reference to the chapter of his book